Chlorite (sodium salt) CASRN 7758-19-2 | IRIS

IRIS

System	RfD (mg/kg-day)	Basis	PoD	Composite UF	Confidence
Nervous, Developmental	3 x 10 ^-2	Neurodevelopmental effects	NOAEL : 3 mg/kg-day	100	Medium/High

Reference Concentration for Inhalation Exposure (RfC) (PDF) (19 pp, 143 K) Last Updated: 10/12/2000
Information reviewed but value not estimated.

Weight of Evidence for Cancer (PDF) (19 pp, 143 K) Last Updated: 10/12/2000

WOE Characterization	Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Carcinogenic potential cannot be determined	Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996)

Basis:

Under the current guidelines (U.S. EPA, 1986), chlorite is classified as Group D; not classifiable as to human carcinogenicity because of inadequate data in humans and animals. Under the draft Carcinogen Assessment Guidelines (U.S. EPA, 1996), the human carcinogenicity of chlorite cannot be determined because of a lack of human data and limitations in animal studies.
This may be a synopsis of the full weight-of-evidence narrative.

Not assessed under the IRIS Program.

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

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