n-Hexane
CASRN 110-54-3 | DTXSID0021917
- Toxicological Review (PDF) (210 pp, 1.4 M)
- IRIS Summary (PDF) (28 pp, 188 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(28 pp, 188 K)
Last Updated: 12/23/2005
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(28 pp, 188 K)
Last Updated: 12/23/2005
| System | RfC (mg/m3) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous | 7 x 10 -1 | Peripheral neuropathy (decreased MCV at 12 weeks) |
BMCL
(HEC):
215
mg/m3 |
300 | Medium |
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(28 pp, 188 K)
Last Updated: 12/23/2005
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| Inadequate information to assess carcinogenic potential | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005) |
- Under the emGuidelines for Carcinogen Risk Assessment/em (U.S. EPA, 2005b), there is eminadequate information to assess the carcinogenic potential of n-hexane./em
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (28 pp, 188 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (28 pp, 188 K)
Not assessed under the IRIS Program.
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
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