Selenium and Compounds
CASRN 7782-49-2 | DTXSID9021261
- IRIS Summary (PDF) (24 pp, 166 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(24 pp, 166 K)
Last Updated: 06/01/1991
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous, Hematologic, Dermal | 5 x 10 -3 | Clinical selenosis |
NOAEL
:
1.5
x 10-2 mg/kg-day |
3 | High |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(24 pp, 166 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(24 pp, 166 K)
Last Updated: 03/01/1991
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Based on inadequate human data and inadequate evidence of carcinogenicity in animals. The evidence for various selenium compounds in animal and mutagenicity studies is conflicting and difficult to interpret; however, evidence for selenium sulfide is sufficient for a B2 (probable human carcinogen) classification.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (24 pp, 166 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (24 pp, 166 K)
Not assessed under the IRIS Program.
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