Benzo[k]fluoranthene CASRN 207-08-9 | IRIS

IRIS

Reference Dose for Oral Exposure (RfD) (PDF) (8 pp, 97 K) Last Updated:
Not assessed under the IRIS Program.

Weight of Evidence for Cancer (PDF) (8 pp, 97 K) Last Updated: 11/01/1990

WOE Characterization	Framework for WOE Characterization
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)

Basis:

Based on no human data and sufficient data from animal bioassays. Benzo[k]fluoranthene produced tumors after lung implantation in mice and when administered with a promoting agent in skin-painting studies. Equivocal results have been found in a lung adenoma assay in mice. Benzo[k]fluoranthene is mutagenic in bacteria.
This may be a synopsis of the full weight-of-evidence narrative.

Not assessed under the IRIS Program.

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

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