Nitroguanidine
CASRN 556-88-7 | DTXSID4024222
- IRIS Summary (PDF) (11 pp, 107 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(11 pp, 107 K)
Last Updated: 09/01/1989
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Developmental, Other | 1 x 10 -1 | Reduced weight gain in female rats, maternal/ fetal toxicity in rats, and equivocal evidence of developmental toxicity in rabbits |
NOAEL
:
3.16
x 102 mg/kg-day |
3000 | Medium |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(11 pp, 107 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(11 pp, 107 K)
Last Updated: 09/01/1990
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Pertinent data regarding carcinogenicity have not been located in the available literature.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (11 pp, 107 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (11 pp, 107 K)
Not assessed under the IRIS Program.
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