Coke oven emissions
CASRN NA | DTXSID7023984
- IRIS Summary (PDF) (13 pp, 114 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(13 pp, 114 K)
Last Updated:
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(13 pp, 114 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(13 pp, 114 K)
Last Updated: 05/01/1989
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| A (Human carcinogen) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Studies of coke oven workers have shown increased risk of mortality from cancer of the lung, trachea and bronchus; cancer of the kidney; cancer of the prostate; and cancer at all sites combined. In animals, extracts and condensates of coke oven emissions were found to be carcinogenic in both inhalation studies and skin-painting bioassays. The mutagenicity of whole extracts and condensates, as well as their individual components, provides supportive evidence for carcinogenicity.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 114 K)
Not Assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 114 K)
Inhalation Unit Risk:
6.2
x 10-4
per µg/m3
Extrapolation Method: Linearized multistage procedure
Tumor site(s): Respiratory
Tumor type(s): Respiratory cancer (Mazumdar et al., 1975; Land, 1976)
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
You will need Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.
Contact Us to ask a question, provide feedback or report a problem.
