Allyl chloride CASRN 107-05-1 | IRIS

IRIS

Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 139 K) Last Updated:
Not assessed under the IRIS Program.

System	RfC (mg/m³)	Basis	PoD	Composite UF	Confidence
Nervous	1 x 10 ^-3	Functional and histological peripheral neurotoxicity	NOAEL (HEC): 3.6 mg/m³	3000	Low

Weight of Evidence for Cancer (PDF) (13 pp, 139 K) Last Updated: 09/01/1990

WOE Characterization	Framework for WOE Characterization
C (Possible human carcinogen)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)

Basis:

Classification is based on a low (but biologically important) incidence of forestomach tumors in female mice and positive results in a variety of genetic toxicity tests. Allyl chloride is an alkylating agent and structurally related to probable human carcinogens.
This may be a synopsis of the full weight-of-evidence narrative.

Not assessed under the IRIS Program.

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

You will need Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.