Mercury, elemental CASRN 7439-97-6 | IRIS

IRIS

Reference Dose for Oral Exposure (RfD) (PDF) (28 pp, 177 K) Last Updated:
Not assessed under the IRIS Program.

System	RfC (mg/m³)	Basis	PoD	Composite UF	Confidence
Nervous	3 x 10 ^-4	Hand tremor; increases in memory disturbances; slight subjective and objective evidence of autonomic dysfunction	LOAEL (ADJ): 9 x 10^-3 mg/m³	30	Medium

Weight of Evidence for Cancer (PDF) (28 pp, 177 K) Last Updated: 05/01/1995

WOE Characterization	Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)

Basis:

Based on inadequate human and animal data. Epidemiologic studies failed to show a correlation between exposure to elemental mercury vapor and carcinogenicity; the findings in these studies were confounded by possible or known concurrent exposures to other chemicals, including human carcinogens, as well as lifestyle factors (e.g., smoking). Findings from genotoxicity tests are severely limited and provide equivocal evidence that mercury adversely affects the number or structure of chromosomes in human somatic cells.
This may be a synopsis of the full weight-of-evidence narrative.

Not assessed under the IRIS Program.

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

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