Furmecyclox
CASRN 60568-05-0 | DTXSID2024119
- IRIS Summary (PDF) (8 pp, 94 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(8 pp, 94 K)
Last Updated:
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(8 pp, 94 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(8 pp, 94 K)
Last Updated: 09/07/1988
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Dose-related increased incidence of neoplastic nodules, carcinomas and combined neoplasic nodules/carcinomas in the liver of female rats and increased incidence of liver nodules and carcinomas and urothelial tumors of the bladder in male rats.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (8 pp, 94 K)
Oral Slope Factor:
3.0
x 10-2
per mg/kg-day
Drinking Water Unit Risk:
8.6
x 10-7
per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Combined liver nodules and carcinomas (BASF Wyandotte, 1984a)
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (8 pp, 94 K)
Not Assessed under the IRIS Program.
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