Isoxaben CASRN 82558-50-7 | IRIS

IRIS

IRIS Summary (PDF) (12 pp, 110 K)
Status: EPA announced in a 2004 Federal Register Notice that chemicals used as pesticides would not be re-assessed by the IRIS Program. This entry in the IRIS database is preserved at the request of EPA program and regional offices. Additional toxicological information may be found under "Other EPA Information."

System	RfD (mg/kg-day)	Basis	PoD	Composite UF	Confidence
Hepatic, Urinary, Cardiovascular	5 x 10 ^-2	Increased BUN; decreased serum AP and AST; decreased food consumption efficiency; increased heart/body weight	NOEL : 5 mg/kg-day	100	High

Weight of Evidence for Cancer (PDF) (12 pp, 110 K) Last Updated: 09/01/1991

WOE Characterization	Framework for WOE Characterization
C (Possible human carcinogen)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)

Basis:

Based on a statistically significant increased incidence of benign liver tumors in one species.
This may be a synopsis of the full weight-of-evidence narrative.

Not assessed under the IRIS Program.

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

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