IRIS

2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP)

CASRN 93-72-1 | DTXSID0021387

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 103 K) Last Updated: 09/07/1988

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Hepatic 8 x 10 -3 Histopathological changes in liver NOEL : 7.5 x 10-1
mg/kg-day
100 Medium

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 103 K)
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (10 pp, 103 K) Last Updated: 08/22/1988

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Human data are not available and the available animal cancer bioassay studies are considered to be inadequate.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 103 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 103 K)

Not assessed under the IRIS Program.


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