trans-1,2-Dichloroethylene
CASRN 156-60-5 | DTXSID7024031
- Toxicological Review (PDF) (174 pp, 1.18 M)
- IRIS Summary (PDF) (22 pp, 215 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(22 pp, 215 K)
Last Updated: 09/30/2010
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Immune | 2 x 10 -2 | Decrease in number of antibody forming cells (AFCs) against sheep red blood cells (sRBCs) in male mice |
BMDL
1SD
:
65.0
mg/kg-day |
3000 | Low |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(22 pp, 215 K)
Last Updated: 09/30/2010
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(22 pp, 215 K)
Last Updated: 09/30/2010
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| Inadequate information to assess carcinogenic potential | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005) |
- Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005a), there is "inadequate information to assess the carcinogenic potential" of trans-1,2-DCE.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (22 pp, 215 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (22 pp, 215 K)
Not assessed under the IRIS Program.
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