3-Methylphenol
CASRN 108-39-4 | DTXSID6024200
- IRIS Summary (PDF) (16 pp, 125 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(16 pp, 125 K)
Last Updated: 08/22/1988
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous | 5 x 10 -2 | Decreased body weights and neurotoxicity |
NOAEL
:
5.0
x 101 mg/kg-day |
1000 | Medium |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(16 pp, 125 K)
Last Updated: 04/01/1992
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(16 pp, 125 K)
Last Updated: 09/01/1990
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| C (Possible human carcinogen) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Based on an increased incidence of skin papillomas in mice in an initiation-promotion study. The three cresol isomers produced positive results in genetic toxicity studies both alone and in combination.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (16 pp, 125 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (16 pp, 125 K)
Not assessed under the IRIS Program.
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
You will need Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.
Contact Us to ask a question, provide feedback or report a problem.
