Acetone
CASRN 67-64-1 | DTXSID8021482
- Toxicological Review (PDF) (85 pp, 1.19 M)
- IRIS Summary (PDF) (26 pp, 229 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(26 pp, 229 K)
Last Updated: 07/31/2003
System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
---|---|---|---|---|---|
Urinary | 9 x 10 -1 | Nephropathy |
NOAEL
:
900
mg/kg-day |
1000 | Medium |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(26 pp, 229 K)
Last Updated: 07/31/2003
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(26 pp, 229 K)
Last Updated: 07/31/2003
WOE Characterization | Framework for WOE Characterization |
---|---|
Data are inadequate for an assessment of human carcinogenic potential | Revised Draft Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999) |
- In accordance with the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999) data are inadequate for an assessment of the human carcinogenic potential of acetone.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (26 pp, 229 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (26 pp, 229 K)
Not assessed under the IRIS Program.
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