IRIS

Acetone

CASRN 67-64-1 | DTXSID8021482

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (26 pp, 229 K) Last Updated: 07/31/2003

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Urinary 9 x 10 -1 Nephropathy NOAEL : 900
mg/kg-day
1000 Medium

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (26 pp, 229 K) Last Updated: 07/31/2003
Information reviewed but value not estimated.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (26 pp, 229 K) Last Updated: 07/31/2003

WOE Characterization Framework for WOE Characterization
Data are inadequate for an assessment of human carcinogenic potential Revised Draft Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999)
Basis:
  • In accordance with the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999) data are inadequate for an assessment of the human carcinogenic potential of acetone.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (26 pp, 229 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (26 pp, 229 K)

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

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